jak2 p phospho jak Search Results


p jak2  (Proteintech)
96
Proteintech p jak2
Western blotting diagram of the effect of W. coagulans MZY531 postbiotics on the expression of apoptosis signaling pathway proteins. ( A ) Bax, Bcl2, and caspase-3 protein expressions in tumor tissue. ( B – D ) Bax, Bcl2, and caspase-3 protein expression gray value. ( E ) Phosphorylation of <t>JAK2</t> and STAT3 and the expression levels of unphosphorylated JAK2 and STAT3 proteins in tumor tissue. ( F , G ) P-JAK2/JAK2 and P-STAT3/STAT3 protein expression gray value. Statistical analysis was conducted using ANOVA, with subsequent post hoc testing performed via Duncan’s multiple comparison test. Means with different superscript letters (a, b, c, and d) are statistically significantly different from each other ( p < 0.05), with ‘a’ representing the highest value and ‘d’ representing the lowest.
P Jak2, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/jak2+p+phospho+jak/JAK2+Antibody/pmc11509727-67-16-44
Average 96 stars, based on 1 article reviews
p jak2 - by Bioz Stars, 2026-10
96/100 stars
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phospho jak 2  (Santa Cruz Biotechnology)
94
Santa Cruz Biotechnology phospho jak 2
Western blotting diagram of the effect of W. coagulans MZY531 postbiotics on the expression of apoptosis signaling pathway proteins. ( A ) Bax, Bcl2, and caspase-3 protein expressions in tumor tissue. ( B – D ) Bax, Bcl2, and caspase-3 protein expression gray value. ( E ) Phosphorylation of <t>JAK2</t> and STAT3 and the expression levels of unphosphorylated JAK2 and STAT3 proteins in tumor tissue. ( F , G ) P-JAK2/JAK2 and P-STAT3/STAT3 protein expression gray value. Statistical analysis was conducted using ANOVA, with subsequent post hoc testing performed via Duncan’s multiple comparison test. Means with different superscript letters (a, b, c, and d) are statistically significantly different from each other ( p < 0.05), with ‘a’ representing the highest value and ‘d’ representing the lowest.
Phospho Jak 2, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/jak2+p+phospho+jak/Stat5b+Antibody/pm24797627-90-19-24
Average 94 stars, based on 1 article reviews
phospho jak 2 - by Bioz Stars, 2026-10
94/100 stars
  Buy from Supplier
antibodies against phospho jak2  (Cell Signaling Technology Inc)
94
Cell Signaling Technology Inc antibodies against phospho jak2
Structure-activity relationship of KRC-180 derivatives.
Antibodies Against Phospho Jak2, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/jak2+p+phospho+jak/Phospho-Jak+Family+(Tyr1007%2F1008)+Rabbit+mAb/pmc05529941-70-0-45
Average 94 stars, based on 1 article reviews
antibodies against phospho jak2 - by Bioz Stars, 2026-10
94/100 stars
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human jak stat pathway phosphorylation array c1  (RayBiotech inc)
94
RayBiotech inc human jak stat pathway phosphorylation array c1
Structure-activity relationship of KRC-180 derivatives.
Human Jak Stat Pathway Phosphorylation Array C1, supplied by RayBiotech inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/jak2+p+phospho+jak/Human+JAK%2FSTAT+Pathway+Phosphorylation+Array+C1/pm40295072-68-0-17
Average 94 stars, based on 1 article reviews
human jak stat pathway phosphorylation array c1 - by Bioz Stars, 2026-10
94/100 stars
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Image Search Results


Western blotting diagram of the effect of W. coagulans MZY531 postbiotics on the expression of apoptosis signaling pathway proteins. ( A ) Bax, Bcl2, and caspase-3 protein expressions in tumor tissue. ( B – D ) Bax, Bcl2, and caspase-3 protein expression gray value. ( E ) Phosphorylation of JAK2 and STAT3 and the expression levels of unphosphorylated JAK2 and STAT3 proteins in tumor tissue. ( F , G ) P-JAK2/JAK2 and P-STAT3/STAT3 protein expression gray value. Statistical analysis was conducted using ANOVA, with subsequent post hoc testing performed via Duncan’s multiple comparison test. Means with different superscript letters (a, b, c, and d) are statistically significantly different from each other ( p < 0.05), with ‘a’ representing the highest value and ‘d’ representing the lowest.

Journal: Life

Article Title: Anticancer Effects of Weizmannia coagulans MZY531 Postbiotics in CT26 Colorectal Tumor-Bearing Mice by Regulating Apoptosis and Autophagy

doi: 10.3390/life14101334

Figure Lengend Snippet: Western blotting diagram of the effect of W. coagulans MZY531 postbiotics on the expression of apoptosis signaling pathway proteins. ( A ) Bax, Bcl2, and caspase-3 protein expressions in tumor tissue. ( B – D ) Bax, Bcl2, and caspase-3 protein expression gray value. ( E ) Phosphorylation of JAK2 and STAT3 and the expression levels of unphosphorylated JAK2 and STAT3 proteins in tumor tissue. ( F , G ) P-JAK2/JAK2 and P-STAT3/STAT3 protein expression gray value. Statistical analysis was conducted using ANOVA, with subsequent post hoc testing performed via Duncan’s multiple comparison test. Means with different superscript letters (a, b, c, and d) are statistically significantly different from each other ( p < 0.05), with ‘a’ representing the highest value and ‘d’ representing the lowest.

Article Snippet: Following blocking with 5% bovine serum albumin, the membranes were incubated with the appropriate antibodies: β-actin, p-JAK2, STAT3, Bcl-2 and Bax (GeneTex, San Antonio, TX, USA), JAK2, p-STAT3, PI3K, AKT, mTOR and p-mTOR (Bioss, Beijing, China), caspase-3 (Abcam, Cambridge, MA, USA), TGF-β, and SMAD4 (Proteintech, Wuhan, China).

Techniques: Western Blot, Expressing, Phospho-proteomics, Comparison

Structure-activity relationship of KRC-180 derivatives.

Journal: Oncology Letters

Article Title: Characterization of the aminopyridine derivative KRC-180 as a JAK2 inhibitor

doi: 10.3892/ol.2017.6353

Figure Lengend Snippet: Structure-activity relationship of KRC-180 derivatives.

Article Snippet: Antibodies against phospho-JAK2 [p-JAK2; rabbit monoclonal immunoglobulin G (IgG); no. 3776; dilution, 1:1,000], p-STAT3 (rabbit polyclonal IgG; no. 9131; dilution, 1:1,000), p-STAT5 rabbit polyclonal IgG; no. 9351; dilution, 1:1,000) and poly (ADP ribose) polymerase (PARP; rabbit polyclonal IgG; no. 9542; dilution, 1:1,000) were purchased from Cell Signaling Technology, Inc. (Danvers, MA, USA).

Techniques:

Inhibition of JAK2 kinase activity by KRC-180. (A) Chemical structure of KRC-180. (B) In vitro JAK2 kinase activity. The indicated concentrations of KRC-180 were added to purified JAK2 enzyme and the kinase activity was measured using time-resolved fluorescence energy transfer. (C) Docking mode of JAK2 and KRC-180. The crystal structure of JAK2 was taken from the active site of the JAK2 kinase domain (Protein Data Bank entry: 4HGE). The P-loop was removed to allow an improved view of the key interactions with Glu930, Arg938, Asp 939, and KRC-180. JAK2, Janus kinase 2.

Journal: Oncology Letters

Article Title: Characterization of the aminopyridine derivative KRC-180 as a JAK2 inhibitor

doi: 10.3892/ol.2017.6353

Figure Lengend Snippet: Inhibition of JAK2 kinase activity by KRC-180. (A) Chemical structure of KRC-180. (B) In vitro JAK2 kinase activity. The indicated concentrations of KRC-180 were added to purified JAK2 enzyme and the kinase activity was measured using time-resolved fluorescence energy transfer. (C) Docking mode of JAK2 and KRC-180. The crystal structure of JAK2 was taken from the active site of the JAK2 kinase domain (Protein Data Bank entry: 4HGE). The P-loop was removed to allow an improved view of the key interactions with Glu930, Arg938, Asp 939, and KRC-180. JAK2, Janus kinase 2.

Article Snippet: Antibodies against phospho-JAK2 [p-JAK2; rabbit monoclonal immunoglobulin G (IgG); no. 3776; dilution, 1:1,000], p-STAT3 (rabbit polyclonal IgG; no. 9131; dilution, 1:1,000), p-STAT5 rabbit polyclonal IgG; no. 9351; dilution, 1:1,000) and poly (ADP ribose) polymerase (PARP; rabbit polyclonal IgG; no. 9542; dilution, 1:1,000) were purchased from Cell Signaling Technology, Inc. (Danvers, MA, USA).

Techniques: Inhibition, Activity Assay, In Vitro, Purification, Fluorescence

Inhibition of JAK2 phosphorylation in HEL92.1.7 cells. (A) Cells were incubated with the indicated concentrations of KRC-180 for 48 h. (B) The cells were incubated with 10 µM KRC-180 for the indicated time. The phosphorylation levels of JAK2, STAT3 and STAT5 were evaluated using western blot analysis with phospho-specific antibodies. The expression levels of total JAK2, STAT3, and STAT5 are also shown. JAK2, Janus kinase 2; STAT, signal transducer and activator of transcription.

Journal: Oncology Letters

Article Title: Characterization of the aminopyridine derivative KRC-180 as a JAK2 inhibitor

doi: 10.3892/ol.2017.6353

Figure Lengend Snippet: Inhibition of JAK2 phosphorylation in HEL92.1.7 cells. (A) Cells were incubated with the indicated concentrations of KRC-180 for 48 h. (B) The cells were incubated with 10 µM KRC-180 for the indicated time. The phosphorylation levels of JAK2, STAT3 and STAT5 were evaluated using western blot analysis with phospho-specific antibodies. The expression levels of total JAK2, STAT3, and STAT5 are also shown. JAK2, Janus kinase 2; STAT, signal transducer and activator of transcription.

Article Snippet: Antibodies against phospho-JAK2 [p-JAK2; rabbit monoclonal immunoglobulin G (IgG); no. 3776; dilution, 1:1,000], p-STAT3 (rabbit polyclonal IgG; no. 9131; dilution, 1:1,000), p-STAT5 rabbit polyclonal IgG; no. 9351; dilution, 1:1,000) and poly (ADP ribose) polymerase (PARP; rabbit polyclonal IgG; no. 9542; dilution, 1:1,000) were purchased from Cell Signaling Technology, Inc. (Danvers, MA, USA).

Techniques: Inhibition, Phospho-proteomics, Incubation, Western Blot, Expressing